СТЕРЕОНАПРАВЛЕННЫЙ СИНТЕЗ (E)- И (Z)-ИЗОМЕРОВ 8-ХЛОРОКТ-7-ЕН-4-ОНА
Аннотация
Для цитирования:
Шахмаев Р.Н., Сунагатуллина А.Ш., Алиева Р.М., Зорин В.В. Стереонаправленный синтез (E)- и (Z)-изомеров 8-хлорокт-7-ен-4-она. Изв. вузов. Химия и хим. технология. 2017. Т. 60. Вып. 1. С. 40-44.
С использованием селективного твердофазного моноалкилирования этил-3-оксогекса-ноата индивидуальными изомерами 1,3-дихлорпропена и последующего декарбалкоксилирования образующихся хлорвинилпроизводных в оптимизированных условиях Крапчо разработан эффективный метод синтеза изомерно чистых (E)- и (Z)-8-хлорокт-7-ен-4-онов.
Литература
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